The COVID-19 pandemic has shaped the world in various ways over the past few years, and one of the most controversial developments is the discussion surrounding the long-term effects of COVID-19 vaccines. In this blog post, we take a scientific look at the so-called “pandemic of the vaccinated” and examine what the latest scientific findings have to say about it.

The Spike Protein: A Central Factor

The spike protein, produced by mRNA vaccines, is at the center of many discussions. Studies have shown that this protein can persist in the body for an extended period. A study in medRxiv (2025; DOI: 10.1101/2025.02.18.25322379) found that the spike protein could be detected in some cases up to 700 days after vaccination ^1^. Another study in Human Vaccines & Immunotherapeutics confirmed that the S1 component of the spike protein could be detected in CD16+ monocytes up to 245 days after vaccination ^2^.