The spike protein destroys stem cells, subverts immune defense, and accumulates — new research reveals the full extent.
There is a phrase that doctors tell millions of post-COVID and post-vaccination patients: “It will get better on its own.” That phrase is wrong. Current data shows: The spike protein — whether from the virus or the vaccine — does not cause a disease that heals by itself. It causes a progressive, self-reinforcing systemic disorder.
Immunologist Joachim Gerlach and clinician Benjamin Börner have mapped the damage potential of the spike protein across a series of publications and current analyses — from stem cells to immune cells, from lungs to brain. Their findings are alarming.
Six Pathological Features — Found in No Other Coronavirus #
SARS-CoV-2 is not a normal coronavirus. Its spike protein contains six features found in no other known coronavirus, which together explain what we observe as “Long COVID” and “Post-Vac” 1:
1. The Furin Cleavage Site #
Without it, no pandemic. The furin cleavage site opens the spike protein and enables cell entry. When the spike is cleaved, the S1 subunit crosses the blood-brain barrier with particular ease — explaining neurological symptoms like brain fog, visual disturbances, and cognitive impairment 1 2.
2. Seven Amyloidogenic Epitopes (Hammarström Epitopes) #
Swedish researcher Per Hammarström (Linköping University) discovered that the SARS-CoV-2 spike protein contains seven peptide sequences that form amyloid fibrils — the same structures found in Alzheimer’s, Parkinson’s, and prion diseases 3.
These amyloid fibrils:
- Cause microclots (the notorious “microthrombi”)
- Disrupt fibrinolysis (the body can no longer dissolve the clots)
- Accumulate in tissue — in the brain, heart, and blood vessels
Hammarström’s latest study (December 2025, JACS) shows: Two of the seven spike amyloid fibrils directly impair fibrin formation and fibrinolysis — the coagulation system is sabotaged in both directions 4.
3. DC-Sign Binding #
The SARS-CoV-2 spike can bind to DC-Sign — a receptor on dendritic cells. These are the cells that normally coordinate the immune response. When the spike infects them, immune regulation itself is compromised. Similar to HIV 1.
4. Superantigen Motif #
The spike contains a Staphylococcus Enterotoxin B-like (SEB) superantigen motif. This becomes accessible only after furin cleavage and triggers uncontrolled T-cell activation. This explains the excessive inflammatory reactions and MIS-C in children 1 5.
5. Prion-Like Structures #
Prions are misfolded proteins that force healthy proteins to misfold — a chain reaction. The spike protein contains sequences that can exhibit prion-like behavior. The long-term significance is not yet fully understood, but the implications for neurodegenerative diseases are concerning 1.
6. The Virus Uses Gut Bacteria as Host Cells #
One of the most disturbing discoveries: SARS-CoV-2 can replicate in gut bacteria — behaving like a bacteriophage. Brogna et al. demonstrated that the virus replicates in bacterial growth medium, following bacterial growth patterns 6 7.
This explains:
- Why spike protein remains detectable in stool
- Why the microbiome is massively disrupted in Long COVID patients
- Why Bifidobacteria are systematically destroyed
- Why antibiotics can influence viral load in some cases
All Six Features — Present in Omicron Too #
“Omicron is harmless.” This is one of the most dangerous narratives. Gerlach’s analysis shows: All six pathological features are fully present in current Omicron variants 1.
| Feature | Wuhan (WT) | mRNA Vaccine Spike | Omicron (current) |
|---|---|---|---|
| Furin cleavage site | Yes | Yes | Yes |
| Hammarström epitopes | Yes | Yes | Yes |
| DC-Sign binding | Yes | Yes | Yes |
| Superantigen motif | Yes | Yes | Yes |
| Prion structures | Yes | Yes | Yes |
| Bacteriophage behavior | Yes | unclear | Yes |
The damage potential of the spike protein has not diminished. What has changed is the ability of current variants to completely escape the immune response.
The Antibodies No Longer Work #
Gerlach’s most recent work (“Antibody Escape and the Drastic Elevation of Circulating Spike Protein Since 2024”) documents the escalation 8:
The new variants are nearly completely antibody-evasive. The antibodies formed through vaccination or prior infection no longer bind to the mutated spike. The virus runs past the immune defense.
The consequence: The spike protein accumulates. Not because the body doesn’t want to fight it, but because it can no longer do so.
MMD Data from Magdeburg Confirms the Escalation #
The MMD laboratory in Magdeburg, which performs spike protein measurements for clinics and physicians across Europe, reports:
| Period | Spike Positivity Rate |
|---|---|
| 2024 (average) | 30-40% |
| 2025 Q1-Q3 | nearly doubled |
| 2025 Q4 | extremely elevated |
The rising positivity rate is not due to more infections, but to the immune system’s inability to clear the spike.
IgG4: The Silent Traitor #
In repeatedly vaccinated individuals, another problem emerges: IgG4 class switching. Normally, the body produces IgG1 and IgG3 antibodies against viral infections — these are aggressive and fight the intruder. After repeated mRNA vaccination, the immune system increasingly produces IgG4 instead 9.
IgG4 is not a fighting antibody. It is a tolerance marker. The body no longer treats the spike protein as an enemy but as “an acquaintance to be tolerated.” The system switches to acceptance.
Clinical signs:
- New food intolerances
- Allergic reactions where none existed before
- Reduced ability to neutralize the virus or spike
- Reduced NK cell activation 9
The Worst Case: Stem Cells Under Attack #
Perhaps the most alarming finding from Gerlach’s research concerns stem cells 1 8.
Every immune cell, every red blood cell, every platelet originates from hematopoietic stem cells in the bone marrow. These stem cells carry the ACE2 receptor — fully expressed. The spike protein can directly enter them.
The problem: Hematopoietic stem cells are finite. They exist only in the thousands in the human body. When they are destroyed, they are not replaced. The furnace goes out.
Risk Hierarchy by Organ System #
| Rank | System | Risk |
|---|---|---|
| 1 | Immune system (bone marrow stem cells) | Highest risk |
| 2 | Lungs (pneumocyte stem cells) | Very high |
| 3 | Gut (epithelial stem cells) | Very high |
| 4 | Bronchi (regeneration) | High |
| 5 | Heart (cardiomyocyte stem cells) | High |
| 6 | Brain (neural stem cells) | Moderate-High |
| 7 | Kidneys | Moderate |
Risk Hierarchy by Immune Cell Type #
| Rank | Cell Type | Risk |
|---|---|---|
| 1 | Hematopoietic stem cells (HSC) | Highest risk |
| 2 | Monocytes / Macrophages | Very high |
| 3 | CD4+ T helper cells | Very high |
| 4 | Dendritic cells | High |
| 5 | Natural Killer cells | High |
| 6 | CD8+ T cells | Moderate |
The CD4 cells — the same cells destroyed in HIV — are also systematically damaged by the spike protein. The TH1/TH2/TH17 system shifts. Gerlach published this observation as early as 2023 2.
P53: The Cancer Defense Is Switched Off #
P53 is the most important tumor suppressor in the human body. A study in Oncotarget (May 2024) shows: The SARS-CoV-2 spike protein disrupts the P53-MDM2 interaction and suppresses the transcriptional activity of P53 10.
This means:
- Cancer cells are no longer detected and eliminated
- Simultaneously, the immune system is weakened by spike damage
- Double effect: Cancer is initiated AND cancer defense is shut down
This explains the observed increase in aggressive cancers — so-called “turbo cancers” — particularly in younger people. Lymphoid and hematopoietic cancers are rising most sharply according to clinical observations.
Why Spontaneous Recovery Is Impossible #
With a normal coronavirus, the body heals itself. The immune defense clears the virus, proteases break down foreign proteins, autophagy recycles damaged cells. With SARS-CoV-2, this doesn’t work — for three reasons:
1. The Spike Hijacks the Body’s Own Defense Mechanisms #
Neutrophil elastase — normally a powerful enzyme that destroys pathogens — does the opposite with the spike: It cleaves it into the highly dangerous amyloidogenic fragments. The body makes the problem worse when it fights it 3 4.
2. The Virus Has a Reservoir #
Through its ability to replicate in gut bacteria 6 7, SARS-CoV-2 has a reservoir that the immune system cannot reach. Spike production can continue even in the absence of active viral infection — via RNA persisting in cells.
3. Stem Cells Are Finite #
When hematopoietic stem cells are destroyed, the body can no longer produce new immune cells. There is no reset button.
4. Vaccinated AND Infected = Worst Case #
The data clearly shows: Patients who were both vaccinated and infected show the most severe and persistent outcomes. The combination of vaccine spike (with lipid nanoparticles, N1-methylpseudouridine, DNA contamination) and viral spike maximizes the damage.
What This Means for Those Affected #
The consequences are clear:
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Waiting doesn’t help. The spike protein does not break down on its own — it accumulates.
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The latency period is deceptive. Some patients develop severe symptoms only after 2-5 years. Being symptom-free today doesn’t necessarily mean being healthy — the system can compensate for a long time before it tips.
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Active detoxification is necessary. Enzymes that proteolytically degrade the spike (nattokinase, bromelain, serrapeptase), binders that clear the fragments, and substances that modulate the immune system — this is not a lifestyle trend, it is a medical necessity.
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Laboratory diagnostics are essential. Anti-spike antibodies (BAU), D-dimers, CRP/IL-6, complete blood count, Vitamin D — measure, don’t guess.
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No further vaccinations. Every additional exposure to spike protein — whether through vaccination or unprotected infection — burdens a system already operating at its limit.
The HIV Comparison Is Not Exaggerated #
Gerlach draws the comparison to HIV deliberately: Both pathogens attack CD4 cells. Both cause progressive immune deficiency. Both can remain asymptomatic for years before the system collapses.
The difference: HIV was taken seriously as a pandemic. For the spike protein, there is officially no problem.
Source for transcription: Interview Joachim Gerlach & Benjamin Börner — YouTube
This article summarizes published and forthcoming research. It is not medical advice. Those affected should seek a physician who takes post-COVID and vaccine injuries seriously — and refuses to be dismissed with “it will get better.”
Sources #
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Gerlach J, Baig AM, Fabrowski M, Viduto V (2023): The immune paradox of SARS-CoV-2. Rev Med Virol. PMID: 36727514 ↩︎ ↩︎ ↩︎ ↩︎ ↩︎ ↩︎ ↩︎
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Gerlach J et al.: Receptor Landscape of SARS-CoV-2 on Immune and Stem Cells. (ResearchGate, forthcoming) ↩︎ ↩︎
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Nyström S, Hammarström P (2022): Amyloidogenesis of SARS-CoV-2 Spike Protein. J Am Chem Soc. DOI: 10.1021/jacs.2c03925 ↩︎ ↩︎
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Nyström S, Hammarström P (2025): SARS-CoV-2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis. PMID: 41295749 ↩︎ ↩︎
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Cheng MH et al. (2020): Superantigenic character of an insert unique to SARS-CoV-2 spike. PNAS. DOI: 10.1073/pnas.2010722117 ↩︎
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Brogna C et al. (2022): Could SARS-CoV-2 Have Bacteriophage Behavior? Vaccines. DOI: 10.3390/vaccines10050708 ↩︎ ↩︎
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Brogna C et al. (2025): Evidence of SARS-CoV-2 bacteriophage potential in human gut microbiota. PMID: 40444030 ↩︎ ↩︎
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Gerlach J et al. (2025): Antibody Escape and the Drastic Elevation of Circulating Spike Protein Since 2024. ResearchGate (Preprint). ↩︎ ↩︎
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Immunity & Ageing (2024): Repeated COVID-19 mRNA vaccination results in IgG4 class switching. PMC11401348 ↩︎ ↩︎
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Oncotarget (2024): SARS-CoV-2 spike S2 subunit inhibits p53 activation. oncotarget.org ↩︎